4 Types of Amyloidosis

I found an interesting article about the four types of Amyloidosis. I hope this might be of help.

The Four Types of Amyloidosis

1. Dialysis Related Amyloidosis or DRA

Dialysis Related Amyloidosis is associated with people on dialysis. The proteins in the blood are too big to be filtered out in the dialysis process and end up getting deposited in the joints and the tendons, causing severe pain, stiffness and fluid build-up in the joints.Dialysis Related Amyloidosis has been associated with Carpal Tunnel Syndrome and is a long-term condition. Newer dialysis equipment is less likely to cause this disease than older equipment.

2. Primary Amyloidosis

Primary Amyloidosis can be caused by bone marrow cancer, but not always. The truth is that no one really knows why this occurs, but what they do know is that the antibodies that are supposed to protect you are somehow not created properly in the bone marrow-so rather than breakdown and get recycled, they build up in the blood and get deposited in various tissues and organs. When this happens, the very antibodies that are supposed to protect you from diseases become the proteins that cause the diease Amyloidosis.

Primary Amyloidosis tends to affect the internal organs such as:

  • Kidney
  • Spleen
  • Liver
  • Lymph Nodes

And cause them to quit functioning the way they are supposed to.

3. Secondary Amyloidosis

Secondary Amyloidosis is associated with Chronic Inflammatory Diseases such as:

  • TB
  • Inflamatory Arthritis
  • Osteomyelities (bone infections)

Like the other forms of Amyloidosis, Secondary Amyloidosis is a build-up of Amyloid proteins in the bloodstream that end up getting trapped inside the tissues and organs causing a lot of pain and other serious problems. When these proteins get trapped inside the internal organs, they can cause the organs to quit functioning normally and even kill you.

4. Hereditary Amyloidosis

The fourth type of Amyloidosis is Hereditary Amyloidosis or Familial Amyloidosis. This type is thought to be inherited and it affects the:

  • Liver
  • Kidneys
  • Heart
  • Nervous system

Although Amyloidosis can affect anyone, the over-all risk factors of all forms of include:

  • Age-over 60
  • Chronic Inflammation
  • Chronic Infection

The most common treatment for this disease is DMSO (dimethyl sulfoxide), which is what is also the common treatment for many types of bladder infections. Dmso is an organic sulfer compound that was first discovered as a by-product of paper manufacturing in 1866. It was first used as a treatment for illnesses in 1963, and is used primarily as a pain medication. Surprisingly, there have been very few controlled studies concerning this drug, although it is FDA approved.

If you have been on dialysis and have Amyloidosis, contact your attorney and ask her what your options are.

Source: http://voices.yahoo.com/the-four-types-amyloidosis-11959013.html?cat=5

My Mom had Primarly Amyloidos. Yes there are 4 types.

I think the treatment information may be out of date on this article. DMSO was the first line of treatment in the 1980s, but there have been breakthroughs since with chemo and stem-cell transplantation.

In addition, familial ATTR amyloidosis can now be cured with liver transplantation. This option requires an accurate diagnosis of the specific protein that causes the disease.